Glaucoma and ocular surface: Review

Glaucoma is the leading cause of blindness worldwide. Ocular surface disease (OSD) is commonly found with glaucoma and could be initiated or exacerbated by topical glaucoma treatments. The preservative agents are important in multidose drugs. The main etiological factor of OSD is preservative agents. OSD with normal and glaucomatous people are evaluated frequently with diagnostic testing including clinical examination and questionnaires to explain the visual function and quality of life. Glaucoma treatments can be related with toxicities to the ocular surface, usually because of the preservatives included in the eye drops; however, the incidence of toxicity can be decreased with the preservative-free medications, or decreased preservative medications, or treatment of dry eye disease. The aim of this review to evaluate the prevalence, causes, and treatment of OSD in glaucoma patients through curent literature, especially those on topical therapy.