A Fatal Case of Opioid Body Packer Syndrome Presented with Seizures

“Body packing” is concealing drugs filled in packets inside the body to traffic illicit drugs. Packets may leak and rupture which may cause drug-induced toxic effects. We present a case of a 25-year-old male patient brought to the Emergency Department due to having a seizure during an international flight. He was diagnosed with status epilepticus and a tracheal intubation was performed but he had a cardiac arrest shortly after. Pinpoint pupils and unclear patient history led to the administration of naloxone. After the successful CPR, the patient was examined with a computed tomography scan which revealed multiple foreign bodies in the distal bowels. The blood toxicology tests were positive for opiates and were negative for heroin metabolites, amphetamine, cocaine, barbiturate, and benzodiazepine. An emergency colonoscopy was performed, and the patient remained in the Intensive Care Unit for 17 days before he died due to complications of Body Packer Syndrome. Early diagnosis and appropriate management of this rare but potentially fatal diagnosis are vital to improve patient outcomes.