The Predictive Value Of Curb 65 And Pneumonia Severity Index (Psi) In Patient With Covid 19 Pneumonia And Correlation With Laboratory Parameters

INTRODUCTION: COVID 19 pneumonia is a disease with a high mortality rate caused by the SARS-CoV-2 virus. Therefore, it is essential to identify patients at risk for mortality. This study aims to determine the ability of pneumonia scores to predict mortality and correlation with laboratory parameters.
METHODS: 312 pneumonia patients with positive PCR results were included in this single-center retrospective study conducted between 10.03.2020 and 10.06.2020. All data obtained from hospital database, CURB 65 and PSI scores were calculated. ROC Curve Analysis was performed for the prognostic value.
RESULTS: 175 (56.1%) of 312 patients were male and 137 (43.9%) were female; mean age was 58.2±16.1 years. Mortality rate was 16% (n=50). Length of hospital stay was 10.6±6.4 day. CURB-65, PSI and PSI risk class were found to be higher in cases that resulted in mortality compared to those without mortality (p<0.001). CURB 65, PSI, PSI risk classification were positively correlated with, d-Dimer, ferritin and neutrophil lymphocyte ratio (NLR). The area under the ROC (Receiver Operator Characteristics) Curve was 0.851 (95% CI= 0,803-0,899) for PSI, 0.833 (95% CI= 0,779-0,888) for PSI risk class score and 0.795 (95% CI = 0,725-0,865) for CURB-65. In determining mortality; optimal cut-off values were ≥1 for CURB 65 (sensitivity 86.0% specificity 61.1%), ≥86.5 for PSI (sensitivity 82% specificity70.6%), and ≥4 for PSI risk classification (sensitivity 76.0% specificity72.9%).
DISCUSSION AND CONCLUSION: CURB 65, PSI and PSI risk classification were found eligible to use in COVID 19 and combining these scores with laboratory parameters can be useful to determine prognosis.