Journal of Clinical Research in Pediatric Endocrinology

[J Clin Res Pediatr Endocrinol]
J Clin Res Pediatr Endocrinol. 2023; 15(2): 220-224 | DOI: 10.4274/jcrpe.galenos.2021.2021.0153  

An Alternative Route of Treatment in Transient Hypothyroxinemia of Prematurity: Rectal Administration of Levothyroxine

Duygu Tunçel1, Zeynep İnce1, Erhan Aygün2, Asuman Çoban1
1İstanbul University, İstanbul Faculty of Medicine, Department of Neonatology, İstanbul, Turkey
2University of Health Sciences Turkey Faculty of Medicine, Department of Pediatrics, Division of Neonatology, İstanbul, Turkey

Transient hypothyroxinaemia of prematurity (THOP) is a disorder encountered particularly in extremely low birth weight and preterm newborns. In recent years, the survival rates of these babies have increased, owing to the advances in neonatal care, thereby increasing the incidence of THOP. Controversies about the management of this disorder still continues while accompanying morbidites may create difficulties in the treatment of these patients. A preterm baby boy, born at 256/7 gestational weeks with a birthweight of 665 g who developed short bowel syndrome after necrotizing enterocolitis surgery and who was treated with rectal levothyroxine, is presented.

Keywords: Levothyroxine, prematurity, short bowel, rectal


Duygu Tunçel, Zeynep İnce, Erhan Aygün, Asuman Çoban. An Alternative Route of Treatment in Transient Hypothyroxinemia of Prematurity: Rectal Administration of Levothyroxine. J Clin Res Pediatr Endocrinol. 2023; 15(2): 220-224

Sorumlu Yazar: Duygu Tunçel, Türkiye


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